How to Evaluate Nano-Hemp: Particle Size, Testing, Ingredients and Value
What a meaningful particle-size report contains, what a COA proves, and how to compare products without relying on unsupported performance claims.
Start with the particle-size method
Dynamic light scattering estimates the hydrodynamic diameter of structures moving in a dispersion. A useful report identifies the finished product and batch, sample preparation, instrument and method, temperature, replicate count, Z-average, polydispersity index and the full distribution. A single average with no method or distribution is incomplete.
Understand what a COA can prove
A batch-specific certificate of analysis can document the identity, potency and listed contaminant results for the tested sample. It does not establish particle size, stability, bioavailability, onset or clinical benefit. Those questions require separate tests designed for those endpoints.
Compare the finished product
- Match the product lot to its COA and particle-size report.
- Compare current ingredients and serving size, not only the front-label milligrams.
- Calculate cost per serving using the labeled serving count and current price.
- Distinguish ingredient or carrier research from finished-product evidence.
- Look for stability data when size or potency is expected to remain consistent over time.
Selected research
- Bouwstra JA, Ponec M. The skin barrier in healthy and diseased state. Biochim Biophys Acta. 2006. doi:10.1016/j.bbamem.2006.06.021
- Kirk RD, et al. Evaluations of Skin Permeability of Cannabidiol and Its Topical Formulations. Medical Cannabis and Cannabinoids. 2022. doi:10.1159/000526769
- Junaid MSA, et al. In vitro percutaneous absorption studies of cannabidiol using human skin. International Journal of Pharmaceutics. 2022. doi:10.1016/j.ijpharm.2022.121540
- Tijani AO, et al. Delivering therapeutic cannabinoids via skin. Journal of Controlled Release. 2021. doi:10.1016/j.jconrel.2021.05.005
